chemoradiation in nasopharyngeal carcinoma: a 6-year experience in tehran cancer institute
نویسندگان
چکیده
to determine the addition of value of neoadjuvant, concurrent and adjuvant chemotherapy to radiation in the treatment of nasopharyngeal carcinoma with regard to the overall survival (os) and disease free survival (dfs) within a six year period in tehran cancer institute. files of all patients with nasopharyngeal carcinoma treated by radiotherapy with or without concurrent chemotherapy in a curative setting in tehran cancer institute during the period of 1999-2005 were retrospectively reviewed.. a total of 103 patients with nasopharyngeal carcinoma had been treated during the study period with radiotherapy or chemoradiotherapy in our institute. there were 29 (28.2%) females and 74 (71.8%) males. the median age at the time of radiotherapy was 47 years old (range 9-75 years). the patients were followed 2 to 76 months with a median follow-up of 14 months. time of first recurrence after treatment was 3-44 months with a median of 10 months.. survival in 2 groups of patients treated with radiotherapy alone or chemoradiation did not have a significant difference (p>0.1). two-year survival in patients treated with or without adjuvant chemotherapy and had local recurrence after treatment did not have significant difference (p>0.1). two-year survival in patients with or without local recurrence after treatment did not have significant difference (p>0.1). a beneficial affect or a survival benefit of adjuvant/neoadjuvant chemotherapy and concurrent chemoradiation was not observed in iranian patients.
منابع مشابه
Gastrointestinal tumor board: an evolving experience in Tehran Cancer Institute.
Gastrointestinal (GI) cancers are a significant source of morbidity and mortality in Iran, with stomach adenocarcinoma as the most common cancer in men and the second common cancer in women. Also, some parts of Northern Iran have one of the highest incidences of esophageal cancer in the world. Multi-disciplinary organ-based joint clinics and tumor boards are a well-recognized necessity for mode...
متن کاملRadiotherapy for Ewing sarcoma: A 5 year experience from Iran cancer institute
Background: Ewing Sarcoma Family of Tumors (ESFTs) is the second most common primary tumors of bone in childhood. The decision regarding the optimal modality for achieving local tumor control remains uncertain. The aim of this study was to report the clinical features and outcome as well as reviewing risk factors in patients. Materials and Methods: This retrospective study included 75 ESFTs pat...
متن کاملgastrointestinal tumor board: an evolving experience in tehran cancer institute.
gastrointestinal (gi) cancers are a significant source of morbidity and mortality in iran, with stomach adenocarcinoma as the most common cancer in men and the second common cancer in women. also, some parts of northern iran have one of the highest incidences of esophageal cancer in the world. multi-disciplinary organ-based joint clinics and tumor boards are a well-recognized necessity for mode...
متن کاملTwo decades of experience with ductal carcinoma in situ of the breast in the Cancer Institute of Tehran, Iran.
BACKGROUND Breast cancer screening and higher quality mammography have resulted in an increase in the diagnosis of ductal carcinoma in situ worldwide. We compared the incidence and other factors in our cases of ductal carcinoma in situ between two recent decades. MATERIALS AND METHODS Medical records of cases of ductal carcinoma in situ who had been admitted to the surgery wards of the Cancer...
متن کاملTreatment of nasopharyngeal carcinoma by tomotherapy: five-year experience
PURPOSE To analyze of survival curve and toxicity outcomes for patients treated for nasopharyngeal carcinoma (NPC) by intensity-modulated radiotherapy (IMRT) delivered by helical TomoTherapy (HT). MATERIALS AND METHODS Since May 2006, 72 patients with primary NPC were treated. In 67 cases PET-CT was used to help delineate the gross tumor volume (GTV); in 4 of these cases distant metastases in...
متن کاملNeoadjuvant Chemoradiation in Squamous Cell Carcinoma of the Maxillary Sinus: A 26-Year Experience
Background. The aim of our study was to evaluate the effects of neoadjuvant platinum-based radiochemotherapy (RCT) in patients with maxillary sinus squamous cell carcinoma and to compare the results with other multimodality treatment concepts for advanced-stage maxillary sinus carcinoma in the literature. Methods. In total, 53 patients with squamous cell carcinoma of the maxillary sinus were re...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
acta medica iranicaجلد ۴۹، شماره ۱، صفحات ۴۹-۵۳
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023